18-year-old George Lass (Ellen Muth) dies when a toilet from the MIR space station falls from the sky and hits her. Upon her death she discovers that she has been slated to become a reaper, a figure who removes souls from others just before death to ease them into thier individual afterlives. Rube (Mandy Patinkin), her new boss in the afterlife introduces her to fellow reapers Roxy (Jasmine Guy), Mason (Callum Blue), and Betty (Rebecca Gayheart). In addition to reaping George discovers she must find a way to support herself in the afterlife and takes a job at a temp agency working for Delores Herbig (Christine Willes) where she had worked at the time of her death. The series also follows the continuing drama of how George's family is dealing with her death as she follows the lives of her mother Joy (Cynthia Stevenson), father Clancy (Greg Kean) and sister Reggie (Britt McKillip).